Research Methods for Clinical Practice Guidelines
KCE Reports 411C (2026)
Summary
How to cite this document?
Jespers Vicky, Verleye Leen, Costa Elena, Vlayen Joan, Struyf Thomas. KCE Process Note: Research Methods for guidelines – update 2025. Methods. Brussels. Belgian Health Care Knowledge Centre (KCE). 2026. KCE Reports 411. (DOI: 10.57598/R411C)
Table of Contents
- Introduction
- general aspects of guideline developments
- Defining the scope and developing review questions
- Critical appraisal of the literature
- GRADE for interventions
- GRADE for diagnostic tests and test-treatment management strategies
- Recommendations
- Review and validation
- Dissemination
- Manual KCE - Validated assessment tools
Files
- Open the Process Note (.PDF, 132p., 3,47 MB)