KCE ProcessBook

Responsible use of AI

Guidance (2026)

Summary

The integration of Artificial Intelligence (AI), into workflows at the Belgian Health Care Knowledge Centre (KCE) presents both opportunities and risks. This guidance aims to support KCE staff, collaborators, and contractors in using AI tools responsibly and securely.

Key points

Responsible use of Artificial Intelligence at KCE is based on the following principles:
• Complete human oversight: AI can assist but not replace your judgment. You must review and take full responsibility for any AI-generated output before using or sharing it.
• Confidentiality: Always protect sensitive information. Use only AI tools with strong data protection (e.g. Microsoft Copilot 365 with KCE license), and never share personal data with any external AI tool.
• Transparency: If AI is used in a substantial and intentional way, disclose it clearly in reports, publications, and presentations, following the provided guidance.
• Proportionality & Environmental Awareness: Use AI only when it adds real value. Avoid using it for trivial tasks, design prompts carefully, and consider the environmental impact of each query.
• Legality: AI use should comply at all times with applicable European and Belgian law, in particular the EU Artificial Intelligence Act, the General Data Protection Regulation, copyright and intellectual property legislation and, where relevant, sector-specific healthcare regulations

How to cite this document?

Costa E, Bourgeois J, Camberlin C, Chalon P, de Meester C, Devriese S, D’Hollander K, Fairon N, Hourlay L, Van Deynse H, Vinck I. Responsible use of AI at KCE: a guidance. Brussels: Belgian Health Care Knowledge Centre (KCE). 2026.

Table of Contents

  1. Introduction
  2. Methods
  3. Guidance
    • Complete human oversight
    • Confidentiality
    • Transparency
    • Proportionality and environmental awareness
  4. Reviews and updates
  5. References

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