3.4. Implications of the classification

Only outcomes considered critical (rated 7—9) or important (rated 4—6) should be included in the evidence profile.

Only outcomes considered critical (rated 7—9) are the primary factors influencing a recommendation and should be used to determine the overall quality of evidence supporting this recommendation.

When determining which outcomes are critical, it is important to bear in mind that absence of evidence on a critical outcome automatically leads to a downgrading of the evidence.