1.3. Steps in the process
Author(s)
GRADE includes the following steps:
- Ask a specific healthcare question to be answered by a recommendation;
- Identify all important outcomes for this healthcare question;
- Judge the relative importance of outcomes;
- Summarize all relevant evidence;
- Grade the quality of evidence for each outcome and for each comparison;
- Decide on the overall quality of evidence across outcomes;
- Include judgments about the underlying values and preferences related to the management options and outcomes;
- Decide on the balance of desirable and undesirable effects;
- Decide on the balance of net benefits and cost;
- Grade the strength of recommendation;
- Formulate a recommendation;
- Implement and evaluate.
The steps are visualized in the following flowchart:
